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Drug Metabolism/Transport and Pharmacokinetics
This comprehensive scientific volume serves to highlight the complex mechanisms governing drug-metabolizing enzymes and drug transporters that dictate the overall pharmacokinetic features of both therapeutic pharmaceuticals and natural herbal medicines. Integrating advanced in vitro and in vivo models, the book examines severe pharmacokinetic alterations and drug-drug interactions triggered by the inhibition or induction of metabolic pathways under specific disease states or through the coadministration of multiple compounds. Furthermore, it addresses cutting-edge methodologies in population pharmacokinetics and microenvironmental tissue profiling to optimize patient-specific dosing regimens. Ultimately, this research collection serves as an indispensable reference framework for pharmacologists, medicinal chemists, and clinical pharmacists striving to enhance drug efficacy and prevent adverse pharmaceutical toxicities.
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